(S)-Timolol maleate ( Timolol maleate )

Catalog No. M13824 CAS No. 26921-17-5

A potent non-selective β-adrenergic receptor antagonist with Ki of 1.97 and 2 nM for β1 and β2 receptor, respectively.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

(S)-Timolol maleate
Note

Research use only, not for human use.
Brief Description

A potent non-selective β-adrenergic receptor antagonist with Ki of 1.97 and 2 nM for β1 and β2 receptor, respectively.
Description

A potent non-selective β-adrenergic receptor antagonist with Ki of 1.97 and 2 nM for β1 and β2 receptor, respectively.Hypertension Approved
Synonyms

Timolol maleate
Pathway

Angiogenesis
Target

Adrenergic Receptor
Recptor

β1-adrenergicreceptor;β2-adrenergicreceptor
Research Area

Cardiovascular Disease
Indication

Hypertension

Chemical Information

CAS Number

26921-17-5
Formula Weight

432.49
Molecular Formula

C17H28N4O7S
Purity

>98% (HPLC)
Solubility

DMSO: ≥ 4.4 mg/mL
SMILES

CC(C)(C)NC[C@@H](COC1=NSN=C1N2CCOCC2)O.C(=C\C(=O)O)\C(=O)O
Chemical Name

2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2S)-, (2Z)-2-butenedioate (1:1)

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Mandagere AK, et al. J Med Chem. 2002;45(2):304-11.
2. Aggarwal D, et al. Int J Pharm. 2005 Feb 16;290(1-2):155-9.
3. Borok J, et al. Br J Dermatol. 2017 Aug 3. doi: 10.1111/bjd.15865.

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