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(S)-Timolol maleate

CAS No. 26921-17-5

(S)-Timolol maleate ( Timolol maleate )

Catalog No. M13824 CAS No. 26921-17-5

A potent non-selective β-adrenergic receptor antagonist with Ki of 1.97 and 2 nM for β1 and β2 receptor, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (S)-Timolol maleate
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent non-selective β-adrenergic receptor antagonist with Ki of 1.97 and 2 nM for β1 and β2 receptor, respectively.
  • Description
    A potent non-selective β-adrenergic receptor antagonist with Ki of 1.97 and 2 nM for β1 and β2 receptor, respectively.Hypertension Approved
  • Synonyms
    Timolol maleate
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    β1-adrenergicreceptor;β2-adrenergicreceptor
  • Research Area
    Cardiovascular Disease
  • Indication
    Hypertension

Chemical Information

  • CAS Number
    26921-17-5
  • Formula Weight
    432.49
  • Molecular Formula
    C17H28N4O7S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 4.4 mg/mL
  • SMILES
    CC(C)(C)NC[C@@H](COC1=NSN=C1N2CCOCC2)O.C(=C\C(=O)O)\C(=O)O
  • Chemical Name
    2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (2S)-, (2Z)-2-butenedioate (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mandagere AK, et al. J Med Chem. 2002;45(2):304-11.
2. Aggarwal D, et al. Int J Pharm. 2005 Feb 16;290(1-2):155-9.
3. Borok J, et al. Br J Dermatol. 2017 Aug 3. doi: 10.1111/bjd.15865.
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